The Church of Santi Apostoli is located in the historic center of Orvieto and has become one of the exhibition halls of the Museo MODO. The church hosts an important exhibition about the painter Luca Signorelli.
The church has three naves, and its facade remains incomplete; in the oratory there is a valuable picture painted from the local artist Vincenzo Pasqualoni, that is a representative work of the Immaculate Conception with the Apostles Philip (Filippo) and James (Giacomo). These two apostles give the name at the church.